Goes to show how easily medication can play havoc with our sex lifes. I took SSRI anti depressants for a year as they were supposed to help my fibromyalgia pain. I cannot remember them changing my pain much but I just trusted that the doc knew what he was doing. For that year I reeeeally struggled to orgasm. Even on my own. I just felt....numb! I did not associate it with the medication for a while (Hence the year of taking them) but about 2/3 months after coming off them, my orgasm and sensation returned. Almost. I ended up with a bit of a mental association that every time my partner would try to please me, it would fail and that build up a lot of feelings of failure and that I was just too difficult, so even today, a few years later, I still get that mental block. Especially if anything is off, like I feel less horny than usual, or I am feeling a bit tired and then I cannot "perform" due to the mental association. Bah! Luckily this happens only like 20% of the time nowadays, so we still have lots of fun.
I will never take SSRI's again though.
They also had the same effect on one of my male friends. He went to the doc as he was feeling depression and they gave him pills and within a week, he could not get his erection. Luckily for him, he knew right away it was the pills and stopped them straight away. He commented that he went to the doc for depression and they took away his one last ability to have fun..fuck that ...he said!
However, they do not have that effect on everyone and if you need to take them then it is best you take them for your overall health than suffer without help.